How Does Mysimba Work?
Mysimba is a slow-release tablet containing two active ingredients:
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Naltrexone – affects the brain’s reward system, reducing cravings.
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Bupropion – supports appetite control and energy balance.
Together, these ingredients help regulate hunger, decrease overeating, and improve overall weight management.
Benefits of Mysimba Tablets
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Reduces appetite and food cravings.
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Helps you feel satisfied with smaller meals.
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Effective when combined with diet and exercise.
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Can lower the risk of obesity-related conditions such as type 2 diabetes, high blood pressure, heart disease, and stroke.
Who Can Take Mysimba?
Mysimba is suitable for adults who are:
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Living with obesity (BMI ≥ 30), or
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Overweight (BMI ≥ 27) with a related health condition such as diabetes, hypertension, or high cholesterol.
A healthcare provider will need to assess your suitability before prescribing Mysimba.
Where to Buy Mysimba in the UK
Mysimba is a prescription-only medicine, meaning you cannot purchase it without approval from a licensed healthcare professional. Online consultations with registered UK pharmacies can help determine if Mysimba is right for you and provide safe dispensing.
| Medicine Type | Opiate antagonists and antidepressants |
| Mechanism of Action | Interacts with the central nervous system, signaling to the brain that the stomach is full, reducing appetite and cravings. |
| Active Ingredient | Naltrexone and bupropion |
| Effective Within | 1-3 months |
| Pack Size | 112 tablets |
| Strength | 8mg Naltrexone and 90mg bupropion |
Mysimba Alternatives
If Mysimba is not suitable, your healthcare provider may suggest one of the following alternatives:
Weight Loss Injections
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Wegovy (semaglutide) – weekly injection to suppress appetite.
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Mounjaro (tirzepatide) – dual-action weight loss injection.
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Saxenda (liraglutide) – daily injection to regulate hunger.
Weight Loss Pills
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Xenical (orlistat 120mg) – prevents fat absorption, taken with meals.
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Generic Orlistat 120mg – a lower-cost alternative to Xenical.
